Human Volunteers Studies
Workshop
Chair: Professor K Hansson Mild
The session dedicated to human volunteer
studies included presentations from research groups funded by both
the MTHR and Home Office TETRA programmes. These groups are using
human volunteers to study the potential effects of radiofrequency
fields on physiology and performance. Endpoints being investigated
include memory, attention and the electroencephalogram, as well
as labyrinthine function, blood pressure and effects on the cardiovascular
system. Other studies are investigating neuroendocrine levels and
general symptoms. The final study in this session explored the effects
of mobile phone use on driving, and compared the effects of hands-free
phone use with other distracting acts performed while driving.
A number of these studies include volunteers who report increased
sensitivity to the fields from mobile phones. These will investigate
the possibility that a sub-population of people may exist who are
hypersensitive to radiofrequency fields. The majority of the human
volunteer studies are still recruiting volunteers, and an important
issue highlighted during this session was the difficulty in recruiting
sufficient numbers of self-reporting hypersensitive individuals.
There could be many reasons for this, including the perceived health
risks surrounding explicit exposure to radiofrequency fields, and
the difficulty in getting subjects to travel to the relevant laboratories
where testing will occur.
All the human volunteer studies will use the same type of exposure
system to enable direct comparisons to be made between studies.
Previous studies used numerous methods to expose subjects to radiofrequency
fields and this made direct intercomparison more difficult. Therefore
a Standard Human Exposure System was designed and produced. This
was based on a commercially available handset which should be broadly
familiar to many volunteers. These handsets have been delivered
to the relevant groups. The handsets are capable of generating either
GSM 900 MHz or TETRA 400 MHz signals, and they can be used to produce
a variety of modes, including pulsed or continuous wave signals.
Finally a range of specific energy absorption rate (SAR) values
can be set. Overall this flexibility allows comprehensive testing
of the usual frequency and field intensities that users of mobile
phones are exposed to. Due to the design of these handsets both
the experimenter and the subject will remain blind to the exposures
used during the experiments. The handsets are also used in a specific
set position on either side of the head ensuring that there is consistent
exposure across all subjects and studies. This also allows accurate
dosimetry calculations to be made.
The groups working with these exposure systems have undertaken testing
to assess if the exposure system interferes with other electronic
equipment used during the experimental work and to assess if volunteers
can dissociate between the handsets different modes. One of the
groups did note a slight difference in temperature of the handset
when set at different modes and new handsets were supplied to this
group to rectify this problem.
All these studies are still collecting data but since they are being
performed blind, no explicit results could yet be presented. However,
the research group studying the effects of hands-free phone use
while driving has completed its experiments and publication of the
results is expected soon.
Summaries
of the closed sessions of the MTHR Research Seminar - 4th of November
2003 |