Epidemiology Workshop
Chair: Professor P Elliott
Professor Elliott welcomed the speakers and the representatives
of the epidemiological research groups funded under the MTHR programme
to the workshop.
Dr Leeka Kheifets, the Head of the Radiation Programme at the
World Health Organisation (WHO) presented an overview of EMF epidemiological
studies. She noted that although some previous studies had focused
on brain cancers these had suffered from several limitations: crude
dosimetry, low usage and adequate latency period. It was suggested
that future research should focus on a wider range of end points
and that the success of future studies would be dependent on improved
exposure assessment, which would need to be updated as new communications
technology is developed, and methodological work. A comparison
of previous radiofrequency and extremely low frequency (ELF) epidemiological
studies was presented. Dr Kheifets suggested that ELF epidemiological
studies benefited from more sophisticated exposure analysis, a
broader range of outcomes, more studies and more consistent results
compared to the radiofrequency studies. A discussion on dosimetry
methodology followed; this included the suitability of personal
dosimetry meters in different situations.
Professor Hamnerius from Chalmers University of Technology, Sweden
gave a presentation on exposure to radiofrequency radiation from
mobile phones. The factors affecting exposure from mobile phones
were discussed, these factors include; the phone model, the method
of power control employed and whether the network uses discontinuous
transmission (DTX). Further details on the impact of power control
on the mobile phone user’s exposure to radiofrequency radiation
were given. This included a description of a Swedish study that
compared the proportion of time that a mobile phone operates at
maximum power in rural and urban areas. It was noted that mobile
phones in rural areas operated at maximum power for 40% of the
time whilst in urban environments the phone operated at maximum
power 20% of the time. In addition, it was estimated that efficient
power control could reduce the power emitted by the mobile phone
by as much as 100 times. It was noted that all the networks use
full power for a significant proportion of the time. If this can
be fully characterised then it was suggested that calculated exposures
could be adjusted accordingly to improve the accuracy of exposure
assessments. It was estimated that DTX reduced the average power
emitted by the mobile phone by 20 – 40%. If a network does
not use DTX it was suggested that the duration of a phone call,
which could be established by using the billing records, could
be used as an approximation for exposure assessment. The assessment
could be improved if data on the phone model, area of use and network
characteristics were available.
Progress reports on the MTHR funded projects: “A case-control
study of brain tumour and acoustic neuromas in relation to use
of mobile phones” and “UK case control study of adult
brain tumours” were presented to the workshop. It was noted
that the Nordic group that Professor Swerdlow had hoped to collaborate
with had no further funding. The workshop discussed whether, as
young children now use mobile phones this age group should be included
in the study. It was concluded that as childhood and adult cancers
were histologically different and the long latency would result
in very low number of cases in younger age groups, it would not
be practical to include children in the project.
A progress report on “Cohort study of mobile phone users
(pilot study)” was given. The need for a cohort study of
sufficient size and duration was discussed as was the technique
of using a pilot study to develop and test methods for a cohort
study in this area. The research group was keen to explore funding
opportunities for a full cohort study. In addition, Anders Ahlbom
from the Karolinska Institute, Sweden presented work on exposure
assessments in mobile phone cohorts. The relative importance of
individual factors in exposure analysis was discussed. Relevant
factors include: total calling time, number of calls, environment,
time of day, phone model, the use of hands free kits and whether
the mobile phone user is stationary or mobile.
A progress report on the MTHR funded project “A case study
of leukaemia in relation to use of mobile phones” was presented.
The potential for overmatching cases and controls in epidemiological
studies was discussed.
Validation of data was discussed by the workshop. The accuracy
of self-reported phone use was an important issue. The difficulty
in recruiting volunteers for projects could be a major problem
due to low participation rates. Alternative strategies for recruiting
controls could include the use of friends and family, although
such arrangements would need careful consideration.
Summaries of the closed sessions
of the MTHR Research Seminar - 11th of November 2002
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